Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614770 | 1.00 | DRD2 (0.54) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28616498 | 0.83 | HTR1A (0.58) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL29675647 | 0.81 | DRD2 (0.55) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28612182 | 0.81 | DRD2 (0.55) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL29675212 | 0.81 | DRD2 (0.54) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28612645 | 0.81 | DRD2 (0.54) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28610812 | 0.80 | LTA4H (0.58) | DRD2DRD3DRD4LTA4H | |
| SCHEMBL29995464 | 0.80 | LTA4H (0.58) | DRD2DRD3DRD4LTA4H | |
| SCHEMBL29675362 | 0.78 | DRD2 (0.56) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28624567 | 0.78 | DRD2 (0.56) | DRD2HTR1AHTR2ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292515-B | Urea compound containing piperazine group and preparation method and application thereof | 沈阳药科大学 | 2022-05-20 | — | — | CN | disclosed |