Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.44 |
| ▸ | DRD3 | P35462 | 8/20 | 0.44 |
| ▸ | DRD4 | P21917 | 6/20 | 0.44 |
| ▸ | HTR2A | P28223 | 12/20 | 0.44 |
| ▸ | HTR1A | P08908 | 11/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735817 | 1.00 | DRD2 (0.44) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL28735819 | 0.86 | DRD2 (0.51) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL28616498 | 0.83 | HTR1A (0.58) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL28612645 | 0.75 | DRD2 (0.54) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL29675212 | 0.75 | DRD2 (0.54) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL28614770 | 0.69 | DRD2 (0.54) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL29675216 | 0.69 | DRD2 (0.54) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL28910494 | 0.66 | ALDH1A1 (0.41) | — | |
| SCHEMBL1193606 | 0.65 | DRD2 (0.67) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL2782093 | 0.65 | DRD2 (0.71) | DRD2DRD3DRD4HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292515-B | Urea compound containing piperazine group and preparation method and application thereof | 沈阳药科大学 | 2022-05-20 | — | — | CN | disclosed |