Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515119 | 0.83 | CALM1 (0.52) | CALM1ADRA1ACHRM2LMNALTA4H | |
| SCHEMBL5353745 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR | |
| SCHEMBL6483432 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR | |
| SCHEMBL25159 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR | |
| SCHEMBL1954690 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR | |
| SCHEMBL6689612 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR | |
| Diphenylmethane SCHEMBL28532500 | 0.80 | CALM1 (0.67) | CALM1LMNALTA4HSLC6A2SLC6A3 | |
| SCHEMBL517001 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR | |
| SCHEMBL12761516 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR | |
| SCHEMBL6543382 | 0.80 | KDM4E (0.65) | ADRA2CCYP3A4CYP2D6ADRA1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641831-B | Monomers, polymers, preparation method and use thereof | 东莞东阳光医疗智能器件研发有限公司 | 2021-09-10 | — | — | CN | disclosed |