Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL28616995

O=S(=O)(O)C(F)(F)F.Pc1ccncc1

nearest known ligand 0.35

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLOD2 O00469 1/20 0.35
PLOD3 O60568 1/20 0.35
PLOD1 Q02809 1/20 0.35
KIF11 P52732 1/20 0.34
KMT2A Q03164 1/20 0.33
PTGS1 P23219 4/20 0.33
ABCC9 O60706 2/20 0.33
ABCC8 Q09428 2/20 0.33
KCNJ11 Q14654 2/20 0.33
KCNJ8 Q15842 2/20 0.33
NAPRT Q6XQN6 2/20 0.32
HPGD P15428 1/20 0.32
USP2 O75604 1/20 0.31
RAB9A P51151 1/20 0.31
LTA4H P09960 1/20 0.31
PTGS2 P35354 4/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TYK2 P29597 1/20 0.30
SLC22A12 Q96S37 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL5069402 0.81 USP2 (0.45) PLOD2PLOD3PLOD1KIF11KMT2A
Trifluoromethanesulfonic Acid SCHEMBL30504299 0.81 KIF11 (0.50) PLOD2PLOD3PLOD1KIF11KMT2A
Trifluoromethanesulfonic Acid SCHEMBL3991498 0.79 ALDH1A1 (0.38) PLOD2PLOD3PLOD1NAPRTL3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL669548 0.79 PTGS2 (0.42) PLOD2PLOD3PLOD1KIF11KMT2A
Isonicotinonitrile SCHEMBL669363 0.75 SLC22A12 (0.48) KIF11KMT2APTGS1PTGS2SLC22A12
Trifluoromethanesulfonic Acid SCHEMBL5974348 0.75 TDP1 (0.46) PLOD2PLOD3PLOD1RAB9AALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL1377208 0.75 CHRM5 (0.59) KMT2APTGS1HPGDRAB9APTGS2
SCHEMBL9062720 0.74
Trifluoromethanesulfonic Acid SCHEMBL21225256 0.73 NAPRT (0.45) PTGS1NAPRTPTGS2L3MBTL1ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL318231 0.73 NAPRT (0.45) PTGS1NAPRTPTGS2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716367-B Method for preparing 4-mercaptopyridine compound by micro-flow field reactor technology 南京工业大学 2024-04-12 CN disclosed
CN-114716367-A Method for preparing 4-mercaptopyridine compound by virtue of micro-flow field reactor technology 南京工业大学 2022-07-08 CN disclosed
CN-114573658-A Method for realizing pyridine selective functionalization of cysteine and polypeptide thereof by using microchannel reactor 南京工业大学 2022-06-03 CN disclosed
CN-113387876-B Nickel-catalyzed direct reduction cross-coupling method for heterocyclic phosphonium salt and aryl bromide and product 南京工业大学 2022-04-15 CN disclosed
CN-113645971-A Compound and use thereof 福宏治疗公司 2021-11-12 CN disclosed
CN-113387876-A Nickel-catalyzed direct reduction cross-coupling method for heterocyclic phosphonium salt and aryl bromide and product 南京工业大学 2021-09-14 CN disclosed