Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702132 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL14355532 | 0.81 | TERT (0.72) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL28218368 | 0.80 | MAPT (0.58) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL28623250 | 0.79 | RAB9A (0.66) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL9613366 | 0.79 | KDM4E (0.75) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL31312568 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL8358236 | 0.76 | GNG2 (0.73) | KMT2AMEN1 | |
| SCHEMBL15505562 | 0.76 | FABP3 (0.60) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL15642202 | 0.76 | ALDH1A1 (0.76) | ALDH1A1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL22590411 | 0.75 | P2RY14 (0.62) | ALDH1A1KDM4EKMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-113292539-A | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-108026072-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-17 | — | — | CN | disclosed |