Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | IL1B | P01584 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038937 | 0.79 | NR1H2 (0.43) | P2RX7RORC | |
| SCHEMBL30695004 | 0.79 | NR1H2 (0.43) | P2RX7RORC | |
| SCHEMBL17199358 | 0.76 | RORC (0.36) | GAARORC | |
| SCHEMBL10372436 | 0.74 | GAA (0.35) | GAARORCCNR1TOP2A | |
| SCHEMBL21420031 | 0.73 | NOTUM (0.33) | RETKDR | |
| SCHEMBL19875661 | 0.73 | RET (0.33) | RETKDR | |
| SCHEMBL13241454 | 0.72 | ABHD6 (0.43) | CNR1 | |
| SCHEMBL23439990 | 0.71 | P2RX7 (0.34) | RETKDRMAPK14P2RX7 | |
| SCHEMBL23993155 | 0.70 | CNR1 (0.43) | MAPK14CYP17A1RORCCNR1 | |
| SCHEMBL23994521 | 0.69 | HTR3A (0.42) | RETKDRESR1CYP17A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195475-A | Inhibitors of human immunodeficiency virus replication | VIIV保健英国第五有限公司 | 2021-07-30 | — | — | CN | disclosed |