Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30838726 | 1.00 | PDK2 (0.44) | PDK2OPRM1HTTCNR1GPR35 | |
| SCHEMBL28611827 | 0.86 | PDK2 (0.46) | PDK2OPRM1HTTCNR1GPR35 | |
| SCHEMBL30838750 | 0.85 | PDK2 (0.42) | PDK2HTTCNR1GPR35GPR55 | |
| SCHEMBL29161790 | 0.85 | PDK2 (0.42) | PDK2HTTCNR1GPR35GPR55 | |
| SCHEMBL28612399 | 0.81 | PDK2 (0.45) | PDK2OPRM1HTTCNR1GPR35 | |
| SCHEMBL1758080 | 0.81 | OPRM1 (0.42) | PDK2OPRM1OPRK1OPRL1KIF11 | |
| SCHEMBL28624389 | 0.78 | PDK2 (0.49) | PDK2OPRM1CA1CA2CA7 | |
| SCHEMBL7313071 | 0.77 | PDK2 (0.57) | PDK2HTTCA1CA2CA7 | |
| SCHEMBL7320511 | 0.76 | PDK2 (0.47) | PDK2OPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL7315720 | 0.74 | KIF11 (0.46) | PDK2OPRM1OPRK1OPRL1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264883-B | Method for rapidly synthesizing phenanthridine compounds | 中国科学技术大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-113264883-A | Method for rapidly synthesizing phenanthridine compound | 中国科学技术大学 | 2021-08-17 | — | — | CN | disclosed |