Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28606874 | 0.97 | NPEPPS (0.32) | NPEPPSGABRA1GABRB2CRHBPCRHR2 | |
| SCHEMBL28619282 | 0.93 | NPEPPS (0.30) | NPEPPS | |
| Hydrochloric Acid SCHEMBL28622848 | 0.73 | — | — | |
| Bromide SCHEMBL28619298 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28605952 | 0.70 | DPP4 (0.32) | GABRA1GABRB2ANPEPDPP4 | |
| Hydrochloric Acid SCHEMBL29672576 | 0.67 | GABRA1 (0.34) | NPEPPSGABRA1GABRB2CRHBPCRHR2 | |
| Bromide SCHEMBL28619434 | 0.67 | DPP4 (0.32) | GABRA1GABRB2ANPEPDPP4 | |
| SCHEMBL28618056 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28606132 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL2523586 | 0.61 | GABRA1 (0.35) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045533-A | Synthetic method of cyclic carbonate | 南京工业大学 | 2021-06-29 | — | — | CN | disclosed |