SCHEMBL28617847

SCHEMBL28617847

OB(O)c1cc(-c2ccsc2)cs1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.42
CYP2B6 P20813 3/20 0.42
CYP2E1 P05181 2/20 0.42
ERN1 O75460 4/20 0.41
KCNH2 Q12809 1/20 0.40
ACMSD Q8TDX5 1/20 0.38
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
PTPRC P08575 1/20 0.34
PDGFRB P09619 1/20 0.34
PDGFRA P16234 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290331 0.76 MGLL (0.45) CYP2A6CYP2B6CYP2E1
SCHEMBL2556986 0.73 CA2 (0.40)
SCHEMBL2555036 0.73 ALDH1A1 (0.38)
SCHEMBL22734782 0.71 CYP2A6 (0.48) CYP2A6CYP2B6CYP2E1ERN1KCNH2
SCHEMBL2125063 0.71 CYP2A6 (0.72) CYP2A6CYP2B6CYP2E1ERN1KCNH2
SCHEMBL2560661 0.70 ESR2 (0.47) CYP3A4CYP2C9
SCHEMBL2552971 0.70 PDPK1 (0.44) CYP2A6
SCHEMBL14184997 0.69 CYP2A6 (0.52) CYP2A6CYP2B6CYP2E1ERN1KCNH2
SCHEMBL4244869 0.69 CYP2A6 (0.48) CYP2A6CYP2B6CYP2E1ERN1KCNH2
SCHEMBL27605043 0.69 ACMSD (0.45) CYP2A6CYP2B6CYP2E1ERN1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113189175-A Preparation method of molecular imprinting sensor, product obtained by preparation method and application of molecular imprinting sensor 南京大学 2021-07-30 CN claimed
CN-113189175-A Preparation method of molecular imprinting sensor, product obtained by preparation method and application of molecular imprinting sensor 南京大学 2021-07-30 CN disclosed