SCHEMBL28617962

SCHEMBL28617962

C=CC(=O)OC(Cc1ccc(OC)cc1)C(O)c1ccc(OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.47
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
FFAR1 O14842 2/20 0.43
THRB P10828 1/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 1/20 0.39
SLC6A4 P31645 1/20 0.39
TGM2 P21980 1/20 0.38
BCL2A1 Q16548 2/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28629141 0.88 ACACB (0.48) THRB
SCHEMBL28616473 0.84 TEAD1 (0.40) THRBALDH1A1PPARGPPARA
SCHEMBL28616251 0.83 THRB (0.52) THRBALDH1A1SMN1; SMN2TGM2
SCHEMBL28635202 0.82 LDHA (0.47) LDHACYP1A2CYP2D6CYP2C19FFAR1
SCHEMBL28619860 0.82 PPARG (0.42) CYP1A2THRBTSHRPPARGPPARA
SCHEMBL4905380 0.79 LDHA (0.57) LDHAFFAR1THRBALDH1A1TP53
SCHEMBL10608029 0.75 TGM2 (0.47) CYP1A2CYP2D6CYP2C19FFAR1THRB
SCHEMBL3685000 0.74 TGM2 (0.46) CYP1A2CYP2D6CYP2C19FFAR1ALDH1A1
SCHEMBL10499956 0.73 TGM2 (0.45) FFAR1ALDH1A1TSHRTGM2BCL2A1
SCHEMBL28620628 0.72 CYP2D6 (0.58) LDHACYP1A2CYP2D6CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641831-B Monomers, polymers, preparation method and use thereof 东莞东阳光医疗智能器件研发有限公司 2021-09-10 CN disclosed