SCHEMBL28635202

SCHEMBL28635202

C=C(C)C(=O)OC(Cc1ccc(OC)cc1)C(O)c1ccc(OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.47
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 1/20 0.41
FFAR1 O14842 2/20 0.40
ACACB O00763 1/20 0.40
POLB P06746 1/20 0.39
SLC6A4 P31645 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CNR2 P34972 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28624382 0.88 ACACB (0.43) ACACB
SCHEMBL28617970 0.85 ACACB (0.45) CYP1A2CYP2D6ACACBPOLBSMN1; SMN2
SCHEMBL28629138 0.85 ACACB (0.44) ACACBPPARGPPARAALDH1A1
SCHEMBL28621093 0.83 THRB (0.44) POLBPPARASMN1; SMN2NPC1ALDH1A1
SCHEMBL28617962 0.82 LDHA (0.47) LDHACYP1A2CYP2D6CYP2C19FFAR1
SCHEMBL14648180 0.77 MAPT (0.53) LDHACYP1A2CYP2D6CYP2C19MAPT
SCHEMBL7188608 0.74 MAPT (0.50) CYP1A2CYP2D6CYP2C19MAPTACACB
SCHEMBL28729290 0.73 LMNA (0.39) ACACBPPARGPPARA
SCHEMBL12990643 0.73 ELANE (0.50) CYP2C19MAPTACACBNPC1ALDH1A1
SCHEMBL26936568 0.72 MAPT (0.45) CYP1A2CYP2C19MAPTFFAR1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641831-B Monomers, polymers, preparation method and use thereof 东莞东阳光医疗智能器件研发有限公司 2021-09-10 CN disclosed