Fluoride

Fluoride

SCHEMBL28618487

F.F.N#Cc1ccc([N+](=O)[O-])cc1F

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 3/20 0.57
ALDH1A1 P00352 6/20 0.50
LMNA P02545 5/20 0.50
HIF1A Q16665 1/20 0.50
TRPV4 Q9HBA0 1/20 0.47
TSHR P16473 1/20 0.45
GAA P10253 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
MAPT P10636 2/20 0.43
XDH P47989 1/20 0.42
RECQL P46063 1/20 0.42
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
BCL6 P41182 1/20 0.40
BCOR Q6W2J9 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL361867 0.98 VCAM1 (0.59) VCAM1ALDH1A1LMNAHIF1ATRPV4
SCHEMBL25837938 0.98 VCAM1 (0.59) VCAM1ALDH1A1LMNAHIF1ATRPV4
SCHEMBL594390 0.84 VCAM1 (0.64) VCAM1ALDH1A1LMNAHIF1ATSHR
Fluoride SCHEMBL28259583 0.83 VCAM1 (0.68) VCAM1ALDH1A1LMNATSHRGAA
SCHEMBL6153777 0.81 ALOX12 (0.50) VCAM1ALDH1A1LMNATRPV4SMN1; SMN2
SCHEMBL73860 0.81 VCAM1 (0.70) VCAM1ALDH1A1LMNATSHRGAA
SCHEMBL27621933 0.78 ALDH1A1 (0.58) VCAM1ALDH1A1LMNAHIF1ATSHR
SCHEMBL82629 0.78 VCAM1 (0.66) VCAM1ALDH1A1LMNAHIF1ATSHR
SCHEMBL2649443 0.77 VCAM1 (0.48) VCAM1ALDH1A1LMNAHIF1AGAA
SCHEMBL505035 0.76 VCAM1 (0.55) VCAM1ALDH1A1LMNAHIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415301-B Diamine compound and method for producing same 株式会社LG化学 2021-08-17 CN disclosed