Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | BCL6 | P41182 | 1/20 | 0.46 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25837938 | 0.82 | VCAM1 (0.59) | MEN1KMT2AVCAM1ALDH1A1LMNA | |
| SCHEMBL361867 | 0.82 | VCAM1 (0.59) | MEN1KMT2AVCAM1ALDH1A1LMNA | |
| Fluoride SCHEMBL28618487 | 0.81 | VCAM1 (0.57) | MEN1KMT2ABCL6BCORVCAM1 | |
| SCHEMBL11591052 | 0.77 | MAPT (0.40) | KIF11MEN1KMT2ABCL6BCOR | |
| SCHEMBL4957626 | 0.75 | HPGD (0.83) | ALOX12HPGDL3MBTL1KIF11MEN1 | |
| SCHEMBL18289622 | 0.75 | HPGD (0.83) | ALOX12HPGDL3MBTL1KIF11MEN1 | |
| SCHEMBL18289621 | 0.75 | HPGD (0.83) | ALOX12HPGDL3MBTL1KIF11MEN1 | |
| SCHEMBL395942 | 0.75 | HPGD (0.83) | ALOX12HPGDL3MBTL1KIF11MEN1 | |
| SCHEMBL13384748 | 0.74 | BCL6 (0.47) | ALOX12HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL15954408 | 0.74 | MAPT (0.53) | HPGDL3MBTL1MEN1KMT2ABCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | ALOX12 2306/4885HPGD 339/4885L3MBTL1 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.