Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.44 |
| ▸ | HTR2B | P41595 | 8/20 | 0.44 |
| ▸ | HTR2A | P28223 | 7/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166021 | 0.89 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A4ADRB1 | |
| SCHEMBL10841091 | 0.87 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A4ADRB1 | |
| SCHEMBL29659975 | 0.87 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A4ADRB1 | |
| SCHEMBL7897325 | 0.81 | CMA1 (0.43) | HTR2CHTR2BHTR2ASLC6A4ADRB1 | |
| SCHEMBL24359176 | 0.79 | HTR5A (0.39) | HTR2CHTR2BHTR2ASLC6A4SRD5A1 | |
| SCHEMBL10991106 | 0.79 | HTR5A (0.39) | HTR2CHTR2BHTR2ASLC6A4SRD5A1 | |
| SCHEMBL4102066 | 0.78 | HTR2C (0.44) | HTR2CHTR2BHTR2ASLC6A4SRD5A1 | |
| SCHEMBL3118450 | 0.78 | KDM4E (0.47) | HTR2AHTR1AARMEN1KMT2A | |
| SCHEMBL3726820 | 0.78 | ESR2 (0.46) | SLC6A4HTR1ASLC6A2MEN1KMT2A | |
| SCHEMBL13283736 | 0.78 | PNMT (0.50) | HTR2CHTR2BHTR2AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264876-B | Method for selectively catalyzing and hydrogenating aromatic heterocyclic compounds by non-hydrogen participation | 延安大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113264876-A | Method for selectively catalyzing and hydrogenating aromatic heterocyclic compounds by non-hydrogen participation | 延安大学 | 2021-08-17 | — | — | CN | disclosed |