Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623603 | 0.82 | HTR6 (0.44) | HTR6PPARGGPR119MMP13MMP1 | |
| SCHEMBL28615646 | 0.82 | HTR6 (0.43) | HTR6PPARGPPARDPPARAALOX5 | |
| SCHEMBL3330566 | 0.80 | HTR6 (0.50) | HTR6PPARGPPARDPPARABCHE | |
| SCHEMBL17736163 | 0.75 | GPR119 (0.53) | GPR119PDE4BKMT2A | |
| SCHEMBL31593168 | 0.73 | KDM4E (0.52) | HTR6ALOX5 | |
| SCHEMBL31315843 | 0.73 | KDM4E (0.52) | HTR6ALOX5 | |
| SCHEMBL15557373 | 0.73 | MMP13 (0.44) | GPR119MMP13 | |
| SCHEMBL3327338 | 0.73 | HTR6 (0.49) | HTR6BCHEMEN1KMT2A | |
| SCHEMBL3326736 | 0.72 | HTR6 (0.46) | HTR6PPARGGPR119MMP13MMP1 | |
| SCHEMBL1570643 | 0.72 | HTR6 (0.58) | HTR6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336751-A | High-efficiency salt-induced kinase inhibitor and preparation method thereof | 南京谷睿生物科技有限公司 | 2021-09-03 | — | — | CN | disclosed |