Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033716 | 0.84 | GPR84 (0.39) | MAPTGPR84FFAR1LMNAFAAH | |
| SCHEMBL1239842 | 0.80 | GPR84 (0.41) | MAPTGPR84FFAR1 | |
| SCHEMBL3294375 | 0.76 | GPR84 (0.50) | MAPTGPR84FFAR1 | |
| SCHEMBL17099453 | 0.76 | GPR84 (0.50) | MAPTGPR84FFAR1 | |
| SCHEMBL7061809 | 0.74 | GPR84 (0.44) | MAPTGPR84FFAR1LMNACYP2D6 | |
| SCHEMBL5199055 | 0.71 | MAPT (0.56) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL10712293 | 0.71 | MAPT (0.56) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL8772487 | 0.71 | MAPT (0.56) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL228284 | 0.71 | MAPT (0.56) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL3689927 | 0.70 | SPHK1 (0.49) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113260607-A | Modified amine lipids | 英特利亚治疗股份有限公司 | 2021-08-13 | — | — | CN | disclosed |