Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618875 | 0.84 | MAPT (0.47) | GPR84FFAR1MAPTFAAHCNR1 | |
| SCHEMBL1239842 | 0.81 | GPR84 (0.41) | GPR84FFAR1FFAR4ZDHHC7MAPT | |
| SCHEMBL3294375 | 0.77 | GPR84 (0.50) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL17099453 | 0.77 | GPR84 (0.50) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL7061809 | 0.76 | GPR84 (0.44) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL3689927 | 0.71 | SPHK1 (0.49) | — | |
| SCHEMBL22033701 | 0.71 | LMNA (0.41) | GPR84FFAR1FFAR4MAPTPPARD | |
| SCHEMBL17818503 | 0.69 | GPR84 (0.41) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL3419500 | 0.67 | GPR84 (0.37) | GPR84FFAR1LMNA | |
| SCHEMBL2860481 | 0.66 | GPR84 (0.39) | GPR84FFAR1FFAR4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3891127-A1 | MODIFIED AMINE LIPIDS | Intellia Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020118041-A1 | MODIFIED AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |