Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099453 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL7061809 | 0.84 | GPR84 (0.44) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL7438181 | 0.84 | CA2 (0.37) | GPR84FFAR1FFAR4 | |
| SCHEMBL1239842 | 0.80 | GPR84 (0.41) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL3689927 | 0.78 | SPHK1 (0.49) | — | |
| SCHEMBL22033716 | 0.77 | GPR84 (0.39) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL20341607 | 0.76 | GPR84 (0.44) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL2051821 | 0.76 | GPR84 (0.44) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL17818503 | 0.76 | GPR84 (0.41) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL20168856 | 0.76 | FFAR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100086611-A1 | Method for Treating Infectious Organisms Normally Considered to be Resistant to an Antimicrobial Drug | BAXTER INTERNATIONAL INC. (US) | 2010-04-08 | — | — | US | claimed |