Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294375 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL17099453 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL7061809 | 0.77 | GPR84 (0.44) | SPHK1EPHX1 | |
| SCHEMBL1239842 | 0.73 | GPR84 (0.41) | — | |
| SCHEMBL26017783 | 0.73 | SPHK1 (0.57) | SPHK1EPHX1CASP2 | |
| SCHEMBL16618457 | 0.71 | SPHK1 (0.59) | SPHK1EPHX1CASP2 | |
| SCHEMBL22033716 | 0.71 | GPR84 (0.39) | — | |
| SCHEMBL3427647 | 0.71 | SPHK1 (0.54) | SPHK1EPHX1CASP2 | |
| SCHEMBL21941459 | 0.71 | SPHK1 (0.54) | SPHK1EPHX1CASP2 | |
| SCHEMBL8333228 | 0.70 | SPHK1 (0.54) | SPHK1EPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1826225-B1 | Thermoplastically processable polyurethane, method for its manufacture and its application | BAYER MATERIALSCIENCE AG (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-1826225-A2 | Thermoplastically processable polyurethane, method for its manufacture and its application | Bayer MaterialScience AG (DE) | 2007-08-29 | — | — | EP | disclosed |