Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13762701 | 0.90 | KMT2A (0.40) | ALOX15KDM4EL3MBTL1SRCPOLB | |
| SCHEMBL28622905 | 0.82 | TAS1R3 (0.38) | ALOX15ALOX12KDM4EALDH1A1HTT | |
| SCHEMBL510120 | 0.75 | MAPT (0.46) | ALOX15KDM4ESRCPOLBMAPT | |
| Hydrochloric Acid SCHEMBL20740117 | 0.73 | MAPT (0.45) | ALOX15KDM4ESRCPOLBMAPT | |
| SCHEMBL3151639 | 0.73 | SRC (0.41) | ALOX15ALOX12KDM4EL3MBTL1SRC | |
| SCHEMBL7497698 | 0.73 | LDHA (0.38) | LDHAKMT2ATDP1CYP2C19CYP2C9 | |
| SCHEMBL28676835 | 0.73 | ALDH1A1 (0.36) | ALOX15ALOX12L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL3025730 | 0.73 | DHFR (0.36) | ALOX15ALOX12KDM4EL3MBTL1MAPT | |
| SCHEMBL29188156 | 0.72 | NPSR1 (0.53) | KDM4EL3MBTL1POLBHSD17B10ALDH1A1 | |
| SCHEMBL508950 | 0.72 | ALDH1A1 (0.38) | ALOX15ALOX12KDM4EL3MBTL1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321583-A | Preparation method and application of 2, 6-diethyl-4-methyl phenyl malonic acid diester | 利尔化学股份有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-110294768-B | Method for synthesizing pinoxaden through 2, 6-diethyl-4-methyl phenylmalonate | 江苏中旗科技股份有限公司 | 2021-08-27 | — | — | CN | claimed |
| CN-113321583-A | Preparation method and application of 2, 6-diethyl-4-methyl phenyl malonic acid diester | 利尔化学股份有限公司 | 2021-08-31 | — | — | CN | disclosed |