Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619021 | 0.83 | GAA (0.48) | ALDH1A1LMNASMN1; SMN2RAB9AMAPT | |
| SCHEMBL9811509 | 0.81 | RECQL (0.51) | RECQLALDH1A1TP53TDP1LMNA | |
| SCHEMBL9626823 | 0.81 | ALDH1A1 (0.57) | RECQLALDH1A1TP53TDP1LMNA | |
| SCHEMBL9772384 | 0.79 | L3MBTL1 (0.47) | ALDH1A1TDP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL30615184 | 0.79 | RECQL (0.50) | RECQLALDH1A1TP53TDP1LMNA | |
| SCHEMBL27182721 | 0.76 | L3MBTL1 (0.44) | ALDH1A1TDP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL4727831 | 0.75 | MMP2 (0.50) | RECQLALDH1A1TP53TDP1LMNA | |
| SCHEMBL9811504 | 0.75 | ALDH1A1 (0.48) | RECQLALDH1A1TP53TDP1LMNA | |
| SCHEMBL27996094 | 0.74 | ATM (0.53) | ALDH1A1TDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28617108 | 0.74 | RECQL (0.48) | RECQLALDH1A1TP53TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307753-B | Preparation method of thioether derivative | 华侨大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-113307753-A | Preparation method of thioether derivative | 华侨大学 | 2021-08-27 | — | — | CN | disclosed |