Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626823 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9811509 | 0.77 | RECQL (0.51) | ALDH1A1TDP1LMNATP53RECQL | |
| SCHEMBL30615184 | 0.76 | RECQL (0.50) | ALDH1A1TDP1LMNATP53RECQL | |
| SCHEMBL28620157 | 0.75 | RECQL (0.49) | ALDH1A1TDP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4727831 | 0.71 | MMP2 (0.50) | ALDH1A1TDP1LMNACA12CA1 | |
| SCHEMBL28617108 | 0.70 | RECQL (0.48) | ALDH1A1TDP1LMNATP53RECQL | |
| SCHEMBL31258304 | 0.70 | MAPT (0.51) | ALDH1A1TDP1KDM4EHPGDLMNA | |
| SCHEMBL10807674 | 0.70 | RECQL (0.50) | ALDH1A1TDP1GAALMNATP53 | |
| SCHEMBL9702120 | 0.70 | CA2 (0.49) | ALDH1A1TDP1GAAKDM4ECYP1A2 | |
| SCHEMBL9446280 | 0.70 | ALDH1A1 (0.50) | ALDH1A1TDP1GAALMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431122-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| WO-1991000312-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-01-10 | — | — | WO | disclosed |