Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636573 | 1.00 | DAO (0.38) | DAOMEN1KMT2AMAPTHPGDS | |
| SCHEMBL30129611 | 0.81 | HSP90AA1 (0.54) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL28620170 | 0.81 | HSP90AA1 (0.54) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL30129740 | 0.73 | ACHE (0.40) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL28629021 | 0.73 | ACHE (0.40) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL28408658 | 0.73 | DAO (0.52) | DAOMEN1KMT2AMAPTHPGDS | |
| SCHEMBL28617260 | 0.70 | TRPM8 (0.43) | KMT2AMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL30129485 | 0.70 | TRPM8 (0.43) | KMT2AMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9547941 | 0.70 | CES2 (0.62) | DAOMEN1KMT2AHPGDSRAB9A | |
| SCHEMBL21151763 | 0.69 | CHKA (0.36) | MEN1KMT2ACES1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248420-B | Preparation method of 2-acyl-3-ester group indole derivatives | 西北农林科技大学 | 2023-01-17 | — | — | CN | claimed |
| CN-113248420-B | Preparation method of 2-acyl-3-ester group indole derivatives | 西北农林科技大学 | 2023-01-17 | — | — | CN | disclosed |