Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285883 | 0.98 | TDP1 (0.64) | TDP1MAPTMEN1KMT2APOLB | |
| Fluoride SCHEMBL28506026 | 0.96 | MAPT (0.62) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL612535 | 0.82 | TDP1 (0.64) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL8317335 | 0.78 | TDP1 (0.64) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL29358067 | 0.77 | ALDH1A1 (1.00) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL29409289 | 0.77 | MAPT (1.00) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL737722 | 0.77 | MAPT (1.00) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL30293804 | 0.77 | TDP1 (1.00) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL78083 | 0.77 | ALDH1A1 (1.00) | TDP1MAPTMEN1KMT2APOLB | |
| SCHEMBL1970698 | 0.77 | CASP6 (0.39) | TDP1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349032-B | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113185436-A | Preparation method of 4-thiophenyl-o-phenylenediamine | 山东国邦药业有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-111349032-A | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-116496192-B | Preparation method of 4-phenylthio-1, 2-phenylenediamine | 山东国邦药业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116496192-A | Preparation method of 4-phenylthio-1, 2-phenylenediamine | 山东国邦药业有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-111349032-B | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111349032-B | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113185436-A | Preparation method of 4-thiophenyl-o-phenylenediamine | 山东国邦药业有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-113185436-A | Preparation method of 4-thiophenyl-o-phenylenediamine | 山东国邦药业有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-111349032-A | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-111349032-A | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2020-06-30 | — | — | CN | disclosed |