Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | TDP2 | O95551 | 9/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | XDH | P47989 | 3/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.45 |
| ▸ | MPG | P29372 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | YES1 | P07947 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15950982 | 0.83 | APP (0.61) | APPTRPC5MEN1KMT2AHSP90AA1 | |
| SCHEMBL28624602 | 0.81 | TOP1 (0.52) | TDP2TOP1 | |
| SCHEMBL28629193 | 0.80 | TOP1 (0.72) | TDP2TOP1BCHEACHE | |
| SCHEMBL28626463 | 0.74 | TOP1 (0.51) | TDP2MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8545907 | 0.70 | TDP2 (0.59) | TDP2MEN1KMT2AMAPTHPGD | |
| SCHEMBL15951016 | 0.68 | GAA (0.47) | APPTRPC5MEN1KMT2AHSP90AA1 | |
| SCHEMBL17912291 | 0.67 | TDP2 (0.90) | TDP2MAPTLMNA | |
| SCHEMBL1520210 | 0.66 | NTRK1 (0.53) | APPMEN1KMT2ACYP3A4MAPT | |
| Datiscetin SCHEMBL43916 | 0.66 | APP (1.00) | APPTRPC5MEN1KMT2AHSP90AA1 | |
| Datiscetin SCHEMBL29737517 | 0.66 | APP (1.00) | APPTRPC5MEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484617-B | Novel benzofuran azanaphthalene dione derivative and preparation method thereof | 爱斯特（成都）生物制药股份有限公司 | 2021-08-31 | — | — | CN | disclosed |