Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NSD2 | O96028 | 3/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | S100A4 | P26447 | 4/20 | 0.55 |
| ▸ | CDC25B | P30305 | 3/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347884 | 0.80 | GAA (0.62) | TDP2MEN1KMT2ANSD2PAX8 | |
| SCHEMBL5915065 | 0.80 | TDP2 (0.81) | TDP2MEN1KMT2ANSD2PAX8 | |
| SCHEMBL7809098 | 0.78 | TDP2 (0.59) | TDP2MEN1KMT2ANSD2PAX8 | |
| SCHEMBL5915061 | 0.78 | GAA (0.86) | TDP2MEN1KMT2ANSD2PAX8 | |
| SCHEMBL9267635 | 0.76 | TDP2 (0.74) | TDP2MEN1KMT2ANSD2PAX8 | |
| Quinizarin SCHEMBL29385801 | 0.75 | MEN1 (1.00) | TDP2MEN1KMT2ABLMTDP1 | |
| Quinizarin SCHEMBL160038 | 0.75 | MEN1 (1.00) | TDP2MEN1KMT2ABLMTDP1 | |
| SCHEMBL460433 | 0.75 | TDP2 (1.00) | TDP2MEN1KMT2ANSD2PAX8 | |
| Phanquone SCHEMBL462025 | 0.75 | MEN1 (1.00) | TDP2MEN1KMT2ANSD2PAX8 | |
| Phanquone SCHEMBL7633567 | 0.75 | MEN1 (1.00) | TDP2MEN1KMT2ANSD2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639183-B1 | NITROGEN OXIDES OF AZA- AND DIAZA-ANTHRACENEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA (IT) | 1998-07-01 | — | — | EP | disclosed |
| EP-0639183-A1 | NITROGEN OXIDES OF AZA- AND DIAZA-ANTHRACENEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992015566-A1 | NITROGEN OXIDES OF AZA- AND DIAZA-ANTHRACENEDIONE DERIVATIVES AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-09-17 | — | — | WO | disclosed |