Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 18/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629193 | 0.85 | TOP1 (0.72) | TOP1TDP2 | |
| SCHEMBL28621891 | 0.81 | APP (0.49) | TOP1TDP2 | |
| SCHEMBL3270938 | 0.74 | TERT (0.52) | TOP1TERT | |
| SCHEMBL28626463 | 0.73 | TOP1 (0.51) | TOP1TDP2 | |
| SCHEMBL15942094 | 0.72 | TOP1 (0.55) | TOP1TERT | |
| SCHEMBL15950982 | 0.65 | APP (0.61) | — | |
| SCHEMBL17912288 | 0.63 | TDP2 (1.00) | TDP2 | |
| SCHEMBL17918933 | 0.62 | TDP2 (0.80) | TDP2 | |
| SCHEMBL8545907 | 0.61 | TDP2 (0.59) | TDP2 | |
| SCHEMBL17912291 | 0.61 | TDP2 (0.90) | TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484617-B | Novel benzofuran azanaphthalene dione derivative and preparation method thereof | 爱斯特（成都）生物制药股份有限公司 | 2021-08-31 | — | — | CN | disclosed |