Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641565 | 0.90 | PARP1 (0.34) | PTGS2RAB9ASLC5A1SLC5A2CA1 | |
| SCHEMBL28922708 | 0.74 | HPGD (0.40) | NPSR1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL28624635 | 0.73 | MEN1 (0.36) | MEN1KMT2AHTTRAB9APOLB | |
| SCHEMBL28636244 | 0.72 | HCAR3 (0.33) | HTT | |
| SCHEMBL28641717 | 0.72 | — | — | |
| SCHEMBL28633071 | 0.72 | ATM (0.35) | ALDH1A1 | |
| SCHEMBL28636950 | 0.71 | GLA (0.42) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL28636949 | 0.71 | GLA (0.42) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL28633072 | 0.71 | LMNA (0.33) | LMNAALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL28628722 | 0.70 | MEN1 (0.35) | LMNAALDH1A1NPSR1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232448-B | (E) -chloropropylketene/olefine aldehyde triazole compound and synthesis method thereof | 陕西师范大学 | 2021-09-21 | — | — | CN | disclosed |