Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922708 | 0.89 | HPGD (0.40) | MEN1KMT2AHTTGRM2CYP19A1 | |
| SCHEMBL28621879 | 0.87 | ALOX15 (0.41) | MEN1KMT2AHDAC1MAPTPOLB | |
| SCHEMBL28641565 | 0.83 | PARP1 (0.34) | NPC1RAB9A | |
| SCHEMBL28641717 | 0.78 | — | — | |
| SCHEMBL28636244 | 0.78 | HCAR3 (0.33) | HTT | |
| SCHEMBL28636949 | 0.76 | GLA (0.42) | MEN1KMT2AHTTHDAC1MAPT | |
| SCHEMBL28636950 | 0.76 | GLA (0.42) | MEN1KMT2AHTTHDAC1MAPT | |
| SCHEMBL28622212 | 0.73 | LMNA (0.36) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL28633071 | 0.70 | ATM (0.35) | — | |
| SCHEMBL28633072 | 0.69 | LMNA (0.33) | MEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232448-B | (E) -chloropropylketene/olefine aldehyde triazole compound and synthesis method thereof | 陕西师范大学 | 2021-09-21 | — | — | CN | disclosed |