Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624165 | 0.80 | ALDH1A1 (0.58) | EGLN1ALDH1A1ALOX15HTTSLC40A1 | |
| SCHEMBL28622697 | 0.78 | KDM4E (0.51) | EGLN1ALDH1A1ALOX15HTTMAPT | |
| SCHEMBL27908512 | 0.75 | ALDH1A1 (0.54) | EGLN1ALDH1A1ALOX15HTTMAPT | |
| SCHEMBL20944081 | 0.75 | ALOX15 (0.58) | EGLN1ALDH1A1ALOX15HTTSLC40A1 | |
| SCHEMBL9945612 | 0.75 | LMNA (0.51) | EGLN1ALDH1A1ALOX15HTTSLC40A1 | |
| SCHEMBL27908517 | 0.74 | TDP1 (0.48) | ALDH1A1ALOX15HTTMAPTTDP1 | |
| SCHEMBL2951217 | 0.74 | ALDH1A1 (0.58) | EGLN1ALDH1A1ALOX15HTTSLC40A1 | |
| SCHEMBL27994689 | 0.72 | PSMD14 (0.64) | EGLN1ALDH1A1ALOX15HTTSLC40A1 | |
| SCHEMBL19616631 | 0.72 | HDAC6 (0.73) | HTTMAPTTDP1LMNAHDAC6 | |
| SCHEMBL19616872 | 0.72 | HDAC6 (0.70) | EGLN1ALDH1A1ALOX15HTTSLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214149-B | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-113214149-A | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2021-08-06 | — | — | CN | disclosed |