Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DDT | P30046 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850550 | 0.92 | CCR1 (0.54) | CCR1NPSR1DDTP2RX7 | |
| SCHEMBL2854814 | 0.92 | TP53 (0.47) | CCR1TP53MAPTMEN1NPC1 | |
| SCHEMBL2849956 | 0.90 | CCR1 (0.62) | CCR1MAPTHSP90AA1NPSR1MEN1 | |
| SCHEMBL2853388 | 0.88 | CCR1 (0.48) | CCR1TP53MAPTABCB1MEN1 | |
| SCHEMBL2856294 | 0.88 | CCR1 (0.49) | CCR1ABCB1 | |
| SCHEMBL2856514 | 0.86 | CCR1 (0.49) | CCR1MAPTHSP90AA1NPSR1ABCB1 | |
| SCHEMBL2862714 | 0.86 | TSHR (0.46) | CCR1MAPTP2RX7 | |
| SCHEMBL2854852 | 0.85 | ABCB1 (0.49) | CCR1ABCB1MEN1KMT2A | |
| SCHEMBL2853270 | 0.85 | CCR1 (0.51) | CCR1MAPTHSP90AA1NPSR1NPC1 | |
| SCHEMBL2856356 | 0.84 | ALDH1A1 (0.47) | CCR1TP53MAPTNPSR1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |