Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366281 | 0.84 | BRD4 (0.49) | NOTUMCYP1A2BRD4CREBBPPRMT5 | |
| SCHEMBL7290389 | 0.80 | NOTUM (0.54) | NOTUMCYP1A2KDM4ELMNAL3MBTL1 | |
| SCHEMBL28614218 | 0.76 | NOTUM (0.46) | NOTUMCYP1A2BRD4CREBBP | |
| SCHEMBL29363056 | 0.74 | NOTUM (0.51) | NOTUMCYP1A2 | |
| SCHEMBL20777516 | 0.72 | NPSR1 (0.48) | NOTUMCYP1A2ALDH1A1MEN1LMNA | |
| SCHEMBL23825536 | 0.68 | NOTUM (0.52) | NOTUMCYP1A2 | |
| SCHEMBL3861097 | 0.68 | CYP2C19 (0.53) | CYP1A2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL524005 | 0.68 | NPSR1 (0.54) | CYP1A2KDM4EALDH1A1LMNAHTT | |
| SCHEMBL8366389 | 0.67 | CTSD (0.45) | NOTUMKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24000658 | 0.66 | PARP1 (0.53) | CYP1A2BRD4CREBBPKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302184-A | 1,3, 4-oxadiazolinone compounds and drugs | 日本新药株式会社 | 2021-08-24 | — | — | CN | claimed |
| CN-113302184-A | 1,3, 4-oxadiazolinone compounds and drugs | 日本新药株式会社 | 2021-08-24 | — | — | CN | disclosed |