Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366392 | 0.79 | KDM4E (0.43) | CTSDNOTUMKDM4EALDH1A1POLB | |
| SCHEMBL8368075 | 0.78 | MAPT (0.40) | MAPTHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8366414 | 0.76 | MAPT (0.40) | MAPTALDH1A1POLBKMT2A | |
| SCHEMBL6958154 | 0.73 | KDM4E (0.45) | MAPTNOTUMHPGDHSD17B10KDM4E | |
| SCHEMBL8517107 | 0.72 | TP53 (0.41) | KDM4E | |
| SCHEMBL717950 | 0.69 | HPGD (0.63) | MAPTHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL9658483 | 0.67 | PTPN1 (0.52) | HPGDHSD17B10KDM4EALDH1A1NPSR1 | |
| SCHEMBL9660434 | 0.67 | HPGD (0.54) | HPGDKDM4EALDH1A1POLB | |
| SCHEMBL18394492 | 0.67 | ALDH1A1 (0.68) | NOTUMHSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL29664535 | 0.67 | ALDH1A1 (0.68) | NOTUMHSD17B10KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929089-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |