Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5407237 | 0.84 | MEN1 (0.52) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL2730686 | 0.84 | CA2 (0.37) | GAATSHRALDH1A1KDM4ENOS3 | |
| SCHEMBL3768429 | 0.82 | KMT2A (0.55) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL17092977 | 0.82 | MEN1 (0.41) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL12233216 | 0.80 | RAB9A (0.51) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL10263129 | 0.79 | TSHR (0.42) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL16965427 | 0.79 | MEN1 (0.43) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL20424112 | 0.78 | PRMT5 (0.41) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL25170710 | 0.78 | MEN1 (0.39) | MEN1HPGDKMT2APRMT5WDR77 | |
| SCHEMBL16740962 | 0.78 | RAB9A (0.40) | MEN1HPGDKMT2APRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302184-A | 1,3, 4-oxadiazolinone compounds and drugs | 日本新药株式会社 | 2021-08-24 | — | — | CN | disclosed |