Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112264 | 0.86 | RAB9A (0.44) | CA2CA12CA1CA9CHRM5 | |
| SCHEMBL28622902 | 0.84 | MEN1 (0.40) | GAATSHRALDH1A1KDM4ENOS3 | |
| SCHEMBL30066494 | 0.83 | GAA (0.38) | CA2CA12CA1CA9GAA | |
| SCHEMBL28722507 | 0.81 | TSHR (0.39) | CA2CA12CA1CA9GAA | |
| SCHEMBL28938071 | 0.81 | TSHR (0.39) | CA2CA12CA1CA9GAA | |
| SCHEMBL1873610 | 0.80 | RAB9A (0.43) | CA2CA12CA1CA9CHRM5 | |
| SCHEMBL26824211 | 0.79 | CA2 (0.37) | CA2CA12CA1CA9GAA | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL113765 | 0.77 | TSHR (0.57) | CA2CA12CA1CA9GAA | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL3889276 | 0.77 | TSHR (0.57) | CA2CA12CA1CA9GAA | |
| SCHEMBL1679019 | 0.77 | TSHR (0.57) | CA2CA12CA1CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012054110-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-04-26 | — | — | WO | disclosed |