SCHEMBL28623924

SCHEMBL28623924

CCCCC1CCCN1C.Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.46

Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.46
CYP2D6 P10635 1/20 0.45
ACKR3 P25106 1/20 0.43
ALDH1A1 P00352 1/20 0.40
CASP3 P42574 2/20 0.40
CASP7 P55210 2/20 0.40
CHRM3 P20309 1/20 0.40
DRD2 P14416 1/20 0.40
DRD1 P21728 1/20 0.40
DRD4 P21917 1/20 0.40
DRD5 P21918 1/20 0.40
DRD3 P35462 1/20 0.40
CASP1 P29466 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9057412 0.83 CYP2D6 (0.46) HTR6CYP2D6ACKR3ALDH1A1CHRM3
SCHEMBL28609198 0.82 S1PR1 (0.47) ALDH1A1CHRM3
SCHEMBL14298319 0.82 ALDH1A1 (0.53) HTR6ACKR3ALDH1A1DRD1
Butylcyclohexane SCHEMBL31082847 0.79 CYP1A2 (0.51) CYP2D6ALDH1A1
SCHEMBL28363662 0.78 ACHE (0.55) HTR6CYP2D6ALDH1A1KDM4E
SCHEMBL29251878 0.78 CYP1A2 (0.49) ALDH1A1DRD1
SCHEMBL31719332 0.77 HTR6 (0.48) HTR6CYP2D6ACKR3CASP3CASP7
Trifluoromethanesulfonic Acid SCHEMBL28186590 0.77 S1PR1 (0.43) ALDH1A1CHRM3DRD2DRD1DRD4
SCHEMBL15337622 0.77 CYP1A2 (0.52) ALDH1A1
SCHEMBL294368 0.77 CYP1A2 (0.52) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113277954-B Amino acid metal chelate micro-nano powder and preparation method thereof 英德市匠心新材料股份有限公司 2023-04-28 CN claimed
CN-113277954-A Amino acid metal chelate micro-nano powder and preparation method thereof 英德市匠心新材料股份有限公司 2021-08-20 CN claimed
CN-113277954-B Amino acid metal chelate micro-nano powder and preparation method thereof 英德市匠心新材料股份有限公司 2023-04-28 CN disclosed
CN-113277954-A Amino acid metal chelate micro-nano powder and preparation method thereof 英德市匠心新材料股份有限公司 2021-08-20 CN disclosed