Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Tetraphenylphosphonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraphenylphosphonium SCHEMBL8038474 | 0.84 | CES2 (0.47) | CYP1A2ALDH1A1CYP2C19CYP2D6TSHR | |
| Tetraphenylphosphonium SCHEMBL42616 | 0.77 | HIF1A (0.47) | CYP1A2ALDH1A1CYP2C19CYP2D6TSHR | |
| Tetraphenylphosphonium SCHEMBL17818165 | 0.77 | HIF1A (0.47) | CYP1A2ALDH1A1CYP2C19CYP2D6TSHR | |
| Tetraphenylphosphonium SCHEMBL8143595 | 0.77 | TSHR (0.43) | CYP1A2ALDH1A1CYP2C19CYP2D6TSHR | |
| Tetraphenylphosphonium SCHEMBL1037056 | 0.76 | CA2 (0.42) | CYP1A2ALDH1A1CYP2C19CYP2D6TSHR | |
| Propionic Acid SCHEMBL18577059 | 0.76 | MAPT (0.50) | CYP1A2ALDH1A1CYP2C19CYP2D6TSHR | |
| Tetraphenylphosphonium SCHEMBL4388860 | 0.75 | CA2 (0.46) | CYP1A2ALDH1A1CYP2C19CYP2D6TSHR | |
| Biphenyl SCHEMBL15333645 | 0.75 | SMN1; SMN2 (0.64) | CYP1A2ALDH1A1TSHRFFAR3CES2 | |
| Naphthalene SCHEMBL7096694 | 0.75 | FFAR3 (0.56) | CYP1A2ALDH1A1CYP2C19TSHRFFAR3 | |
| Propionic Acid SCHEMBL9312830 | 0.75 | FFAR3 (0.56) | ALDH1A1CYP2C19TSHRFFAR3CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625731-B | System and method for separating oil product by eutectic solvent | 中国石油化工股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-112625731-A | System and method for separating oil product by eutectic solvent | 中国石油化工股份有限公司 | 2021-04-09 | — | — | CN | disclosed |