SCHEMBL28624943

SCHEMBL28624943

O=C(NC1(C(=O)O)CC1)c1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
HPGD P15428 6/20 0.54
HTT P42858 5/20 0.54
ALDH1A1 P00352 5/20 0.54
HSD17B10 Q99714 4/20 0.54
MAPT P10636 1/20 0.54
TSHR P16473 1/20 0.54
ALOX12 P18054 1/20 0.54
ATM Q13315 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
GAA P10253 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MPO P05164 1/20 0.52
HIF1A Q16665 1/20 0.52
LMNA P02545 6/20 0.51
TP53 P04637 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CXCR5 P32302 3/20 0.49
NPC1 O15118 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1740329 0.82 CTSL (0.53) KDM4EHPGDHTTALDH1A1HSD17B10
SCHEMBL3752257 0.78 LMNA (0.57) GAALMNAMEN1KMT2ACXCR5
SCHEMBL13164041 0.76 PYGL (0.54) HPGDCXCR5POLBPYGL
SCHEMBL30463857 0.71 KDM4E (0.65) KDM4EHPGDHTTALDH1A1HSD17B10
SCHEMBL77381 0.71 CA1 (0.77) KDM4EHPGDHTTALDH1A1HSD17B10
SCHEMBL70688 0.71 KDM4E (0.71) KDM4EHPGDHTTALDH1A1HSD17B10
SCHEMBL1740298 0.70 KCNK3 (0.46) KDM4ESMN1; SMN2TP53MEN1KMT2A
SCHEMBL1976526 0.70 KDM4E (0.48) KDM4EHTTALDH1A1MAPTTSHR
SCHEMBL31191005 0.70 TSHR (1.00) KDM4EHPGDHTTALDH1A1HSD17B10
SCHEMBL15121240 0.70 TSHR (1.00) KDM4EHPGDHTTALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113317322-B Soluble solution containing aryl formamide cyclopropanecarboxylic acid and preparation method thereof 郑州郑氏化工产品有限公司 2022-04-05 CN disclosed
CN-113317322-A Soluble solution containing aryl formamide cyclopropanecarboxylic acid and preparation method thereof 郑州郑氏化工产品有限公司 2021-08-31 CN disclosed