Diphenylether

Diphenylether

SCHEMBL2862514

OC(c1ccccc1)(c1ccccc1)C(O)(c1ccccc1)c1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.60
TSHR P16473 1/20 0.60
NR1H2 P55055 1/20 0.52
BAX Q07812 1/20 0.52
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MAOA P21397 1/20 0.46
PARP10 Q53GL7 1/20 0.43
SRD5A2 P31213 1/20 0.42
AKR1C3 P42330 1/20 0.42
MAOB P27338 1/20 0.41
FFAR1 O14842 1/20 0.39
IDH1 O75874 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39
GSTP1 P09211 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7173455 0.84 CYP1A2 (0.48) TSHRALDH1A1ALOX15
SCHEMBL36629 0.84 CYP1A2 (0.48) TSHRALDH1A1ALOX15
SCHEMBL982540 0.79 ALDH1A1 (0.42) TSHRALDH1A1ALOX15
Diphenylether SCHEMBL27727076 0.79 LTA4H (0.67) LTA4HTSHRNR1H2BAXCA1
Methoxymethane SCHEMBL2856857 0.79 KCNN4 (0.48) TSHRALDH1A1ALOX15
Diphenylether SCHEMBL2461810 0.78 LTA4H (1.00) LTA4HTSHRNR1H2BAXCA1
Diphenylether SCHEMBL12286 0.78 LTA4H (1.00) LTA4HTSHRNR1H2BAXCA1
Diphenylether SCHEMBL4950525 0.78 LTA4H (1.00) LTA4HTSHRNR1H2BAXCA1
Diphenylether SCHEMBL9061108 0.78 LTA4H (1.00) LTA4HTSHRNR1H2BAXCA1
Boric Acid SCHEMBL28618892 0.76 CYP2C19 (0.42) TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597441-B1 METHOD OF PRODUCING A MULTILAYERED PRODUCT TRIP LICENSES BV (NL) 2021-04-28 EP disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10919288-B2 Method of producing a multilayered product PROCRAFT DEVELOPMENT BV (NL) 2021-02-16 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
EP-1655323-A2 Toner composition Xerox Corporation (US) 2006-05-10 EP disclosed
US-6545064-B1 Improved printability and other surface characteristics. AVERY DENNISON CORPORATION 2003-04-08 US disclosed
WO-2001038452-A1 COATING COMPOSITION AVERY DENNISON CORPORATION (US) 2001-05-31 WO disclosed
US-4443495-A ETHYLENICALLY UNSATURATED COMPOUND AND A POLYTHIOL, SCREEN PRINTABLE W. R. GRACE & CO. (US) 1984-04-17 US disclosed
US-4406826-A POLYTHIOL, UNSATURATED MONOMER, METAL W. R. GRACE & CO. (US) 1983-09-27 US disclosed
US-4374963-A Heat curable epoxy-acrylate compositions W. R. GRACE & CO. (US) 1983-02-22 US disclosed
US-4352723-A ULTRAVIOLET RADIATION; PHOTOINITIATOR AND AROMATIC PINACOL W. R. GRACE & CO. (US) 1982-10-05 US disclosed
US-4288527-A Dual UV/thermally curable acrylate compositions with pinacol W. R. GRACE & CO. (US) 1981-09-08 US disclosed
US-4132812-A FREE RADICAL INITIATOR W. R. GRACE & CO. (US) 1979-01-02 US disclosed
US-4117017-A PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4117196-A PHOTOCURABLE IMIDIZABLE POLYENE-POLYTHIOL COMPOSITIONS W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4080484-A POLYAMIDE-ACID OR POLYIMIDE W. R. GRACE & CO. (US) 1978-03-21 US disclosed
US-4020233-A Heat activated ethylenically unsaturated-polythiol compositions W. R. GRACE & CO. (US) 1977-04-26 US disclosed