Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | BAX | Q07812 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020544 | 0.92 | SRD5A2 (0.59) | PARP10LMNAMAPTHPGDKMT2A | |
| SCHEMBL15448720 | 0.92 | SRD5A2 (0.59) | PARP10LMNAMAPTHPGDKMT2A | |
| SCHEMBL2862520 | 0.92 | SRD5A2 (0.59) | PARP10LMNAMAPTHPGDKMT2A | |
| SCHEMBL28319232 | 0.92 | SRD5A2 (0.59) | PARP10LMNAMAPTHPGDKMT2A | |
| SCHEMBL3471102 | 0.90 | MAPT (0.71) | PARP10LMNAMAPTESR1ESR2 | |
| SCHEMBL10486226 | 0.90 | MAPT (0.71) | PARP10LMNAMAPTESR1ESR2 | |
| SCHEMBL8071074 | 0.90 | MAPT (0.71) | PARP10LMNAMAPTESR1ESR2 | |
| SCHEMBL31012104 | 0.90 | MAPT (0.71) | PARP10LMNAMAPTESR1ESR2 | |
| Hydroquinone SCHEMBL10635290 | 0.88 | LMNA (0.75) | LMNAMAPTESR1ESR2HPGD | |
| SCHEMBL145363 | 0.88 | LMNA (0.75) | LMNAMAPTESR1ESR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170260328-A1 | Methods for Solid Freeform Fabrication | RICOH CO., LTD. (JP) | 2017-09-14 | — | — | US | disclosed |
| US-9695280-B2 | Methods for solid freeform fabrication | RICOH CO., LTD. (JP) | 2017-07-04 | — | — | US | disclosed |
| EP-3147304-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2017-03-29 | — | — | EP | disclosed |
| EP-3144336-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2017-03-22 | — | — | EP | disclosed |
| US-20160257783-A1 | Methods for Solid Freeform Fabrication | RICOH CO., LTD. (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-3049457-A1 | POLYMERIC MATERIAL | Victrex Manufacturing Limited (GB) | 2016-08-03 | — | — | EP | disclosed |
| EP-3049457-A1 | POLYMERIC MATERIAL | Victrex Manufacturing Limited (GB) | 2016-08-03 | — | — | EP | disclosed |
| US-20160208045-A1 | POLYMERIC MATERIAL | VICTREX MANUFACTURING LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| US-20160208045-A1 | POLYMERIC MATERIAL | VICTREX MANUFACTURING LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| EP-2027182-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007144615-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| EP-0428743-B1 | POLY(ARYLENE ETHER KETONE), METHOD OF ITS PRODUCTION, AND ITS USE | TEIJIN LTD (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5290906-A | Polymers from hydroquinone and 2,6-bisUp-fluorobenzoyle naphthalene for films and fibers with tensile strength | TEIJIN LIMITED (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5191056-A | Molding materials | TEIJIN LIMITED (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0428743-A1 | POLY(ARYLENE ETHER KETONE), METHOD OF ITS PRODUCTION, AND ITS USE | TEIJIN LIMITED (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0193187-B1 | PROCESS FOR PREPARING CRYSTALLINE AROMATIC POLYETHERKETONES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-06-13 | — | — | EP | disclosed |
| EP-0354377-A2 | Process for the preparation of aromatic polyether ketones | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |
| US-4757126-A | Polycondensing 4,4'-dihydroxybenzophenone or hydroquinone with dihalogenoaromatic ketone in solvent in the presence of an alkali | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0193187-A1 | Process for preparing crystalline aromatic polyetherketones | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | PKM, KCNK10, KCNK9 | PARP10 1726/4885LMNA 1173/4885MAPT 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.