SCHEMBL2047299

SCHEMBL2047299

C=Cc1cccc(C)c1OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
NFE2L2 Q16236 5/20 0.39
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
DRD2 P14416 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 3/20 0.34
CYP1A1 P04798 2/20 0.34
CYP1B1 Q16678 2/20 0.34
PRMT1 Q99873 1/20 0.34
CYP19A1 P11511 1/20 0.34
SCN4A P35499 2/20 0.33
MAPT P10636 1/20 0.33
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16951902 0.87 CA1 (0.45) CA1CA2NFE2L2ALDH1A1HSD17B10
SCHEMBL5435773 0.85 ALDH1A1 (0.37) CA1CA2ALDH1A1TSHRHSD17B10
SCHEMBL9760825 0.83 CA1 (0.44) CA1CA2NFE2L2ALDH1A1TSHR
SCHEMBL145464 0.82 ALDH1A1 (0.48) CA1CA2ALDH1A1TSHRHSD17B10
SCHEMBL28625833 0.82 ALDH1A1 (0.34) CA1CA2ALDH1A1TSHRHSD17B10
SCHEMBL57085 0.79 NFE2L2 (0.58) NFE2L2HSD17B10KDM4ECYP1A2CYP1A1
SCHEMBL1597634 0.79 CA1 (0.63) CA1CA2NFE2L2ALDH1A1TSHR
SCHEMBL16952238 0.79 CA1 (0.44) CA1CA2NFE2L2ALDH1A1TSHR
SCHEMBL16253606 0.79 CA1 (0.37) CA1CA2NFE2L2ALDH1A1TSHR
SCHEMBL22476163 0.79 SCN4A (0.38) ALDH1A1TSHRCYP1A2SCN4ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180259850-A1 METHOD FOR FORMING PATTERNED CURED FILM, PHOTOSENSITIVE COMPOSITION, DRY FILM, AND METHOD FOR PRODUCING PLATED SHAPED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2018-09-13 US disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 US disclosed
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NOVOMER, INC. (US) 2017-04-20 US disclosed
US-9580547-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2017-02-28 US disclosed
US-9505878-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2016-11-29 US disclosed
US-20160272761-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-09-22 US disclosed
US-9403861-B2 Salen complexes with dianionic counterions NOVOMER, INC. (US) 2016-08-02 US disclosed
US-20150252145-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2015-09-10 US disclosed
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
US-8956989-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2015-02-17 US disclosed
US-20130144032-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-06-06 US disclosed
US-7964531-B2 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2011-06-21 US disclosed
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2010-02-18 US disclosed
US-7608563-B2 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same MITSUI AGRO CHEMICALS, INC. (JP) 2009-10-27 US disclosed
EP-1426365-B9 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME MITSUI CHEMICALS AGRO INC (JP) 2009-10-21 EP disclosed
EP-1426365-B1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME SANKYO AGRO CO LTD (JP) 2009-07-15 EP disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed
US-4720345-A Semipermeable membranes of modified styrene-based polymers, process for their manufacture and their use ALIGENA AG (CH) 1988-01-19 US disclosed
US-4085165-A ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT BRIDGESTONE TIRE CO., LTD. (JA) 1978-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NCLN, POLN, NCL CA1 497/4885CA2 273/4885NFE2L2 4010/4885
US-20130144032-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 CA1 77/4885CA2 90/4885NFE2L2 521/4885
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same CBR3, DDT, CBR1 CA1 4294/4885CA2 1032/4885NFE2L2 913/4885
US-20160272761-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 CA1 77/4885CA2 90/4885NFE2L2 521/4885
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 CA1 77/4885CA2 90/4885NFE2L2 521/4885
US-20150252145-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 CA1 77/4885CA2 90/4885NFE2L2 521/4885
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same CBR3, DDT, CHRM2 CA1 3575/4885CA2 644/4885NFE2L2 892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.