Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962160 | 0.75 | KDM4E (0.33) | — | |
| SCHEMBL21962238 | 0.74 | NLRP3 (0.33) | — | |
| SCHEMBL22014739 | 0.74 | NLRP3 (0.33) | — | |
| SCHEMBL6766966 | 0.73 | ALDH1A1 (0.33) | LDHALDHBAKR1B1 | |
| SCHEMBL22014365 | 0.71 | NLRP3 (0.38) | — | |
| SCHEMBL24192685 | 0.70 | ADORA2A (0.34) | — | |
| SCHEMBL6764105 | 0.70 | — | — | |
| SCHEMBL16843335 | 0.70 | — | — | |
| SCHEMBL8176820 | 0.68 | FABP3 (0.52) | — | |
| SCHEMBL17935193 | 0.66 | CA1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227055-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |