Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262828 | 0.86 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL27502838 | 0.82 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20257394 | 0.78 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9042764 | 0.78 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL104275 | 0.75 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30984376 | 0.75 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14268630 | 0.75 | KMT2A (0.50) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11263588 | 0.74 | HDAC8 (0.47) | NPC1RAB9ASMN1; SMN2KMT2ACYP2C9 | |
| SCHEMBL11972682 | 0.73 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL38658322 | 0.72 | SCN5A (0.56) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156644-B | Method for synthesizing N-sulfenyl benzyl imine or derivatives thereof from Bunte salt | 南京理工大学 | 2021-09-28 | — | — | CN | disclosed |