Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645365 | 0.78 | ALDH1A1 (0.55) | LMNAALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL28634730 | 0.76 | HTR7 (0.66) | LMNAKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL28626118 | 0.76 | HTR7 (0.66) | LMNAMEN1KMT2AHTR7 | |
| SCHEMBL28625994 | 0.76 | HTR7 (0.41) | LMNAKDM4EALDH1A1HPGDHTR7 | |
| SCHEMBL28923057 | 0.75 | HTR7 (0.52) | LMNAKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28923929 | 0.75 | TDP1 (0.61) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL28627426 | 0.75 | MEN1 (0.67) | LMNAKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL28625935 | 0.75 | HTR7 (0.67) | LMNAKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL28627926 | 0.74 | LMNA (0.50) | LMNAKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL19306082 | 0.72 | HTR7 (0.62) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |