Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634730 | 0.82 | HTR7 (0.66) | ALDH1A1NPSR1HTR7CYP2C19LMNA | |
| SCHEMBL28626118 | 0.82 | HTR7 (0.66) | HTR7LMNAMEN1KMT2A | |
| SCHEMBL28645365 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HTR7CYP1A2CYP2C19GFER | |
| SCHEMBL28923057 | 0.81 | HTR7 (0.52) | ALDH1A1HTR7CYP2C19LMNAMEN1 | |
| SCHEMBL28625935 | 0.80 | HTR7 (0.67) | TDP1MAPTALDH1A1NPSR1HTR7 | |
| SCHEMBL28627426 | 0.80 | MEN1 (0.67) | ALDH1A1NPSR1HTR7CYP2C19LMNA | |
| SCHEMBL28627926 | 0.79 | LMNA (0.50) | ALDH1A1HTR7CYP2C19LMNAMEN1 | |
| SCHEMBL28626504 | 0.75 | LMNA (0.43) | ALDH1A1NPSR1HTR7CYP2C19LMNA | |
| SCHEMBL11054418 | 0.75 | MAPT (0.69) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL11055589 | 0.73 | MAPT (0.81) | TDP1MAPTALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |