SCHEMBL2862671

SCHEMBL2862671

FC(F)(F)c1ccc([C]c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.56
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
TRPV6 Q9H1D0 1/20 0.44
MGLL Q99685 1/20 0.44
MIF P14174 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
EPHX2 P34913 1/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
PLAU P00749 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18142145 0.92 KIF11 (0.68) KIF11ALDH1A1TSHR
SCHEMBL11589984 0.83 KIF11 (0.52) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL2866711 0.82 PDE2A (0.44) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL16747679 0.82 KIF11 (0.56) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL14998069 0.82 KIF11 (0.56) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL63468 0.80 ALDH1A1 (0.67) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL99050 0.78 KIF11 (0.52) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL202305 0.78 PTPN1 (0.55) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL1041507 0.78 KIF11 (0.52) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL2167576 0.78 KIF11 (0.52) KIF11ALDH1A1TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661921-B1 Synthetic lubricating oil and lubricating oil composition thereof MITSUI CHEMICALS INC (JP) 2019-07-17 EP disclosed
EP-3124514-B1 OLEFIN-BASED RESIN, METHOD FOR PRODUCING SAME AND PROPYLENE-BASED RESIN COMPOSITION MITSUI CHEMICALS INC (JP) 2019-07-10 EP disclosed
EP-1632505-B1 ETHYLENE POLYMER MITSUI CHEMICALS INC (JP) 2016-09-07 EP disclosed
US-7795194-B2 Synthetic lubricating oil and lubricating oil composition MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
US-20100069588-A1 PROCESS FOR PRODUCTION OF SYNDIOTACTIC PROPYLENE POLYMER Mitsuri Chemicals Inc. 2010-03-18 US disclosed
EP-2083023-A1 METHOD FOR PRODUCING SYNDIOTACTIC PROPYLENE POLYMER Mitsui Chemicals, Inc. (JP) 2009-07-29 EP disclosed
US-7452946-B2 copolymer with C3 to C10 alpha -olefin; provides a blow-molded product and an extrusion-molded product excellent in moldability, mechanical strength and outward appearance; produced in the presence of a solid catalyst MITSUI CHEMICALS, INC. (JP) 2008-11-18 US disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed
US-20060199925-A1 Ethylene polymer MITSUI CHEMICALS, INC. (JP) 2006-09-07 US disclosed
US-20060116303-A1 decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability MITSUI CHEMICALS, INC. (JP) 2006-06-01 US disclosed
EP-1661921-A1 Synthetic lubricating oil and lubricating oil composition thereof Mitsui Chemicals, Inc. (JP) 2006-05-31 EP disclosed
EP-1632505-A1 ETHYLENE POLYMER Mitsui Chemicals, Inc. (JP) 2006-03-08 EP disclosed