Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629852 | 0.88 | SPR (0.50) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20120108 | 0.85 | KDM4E (0.50) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL29123527 | 0.85 | PLA2G2A (0.46) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL28621882 | 0.84 | SPR (0.51) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL28626501 | 0.84 | SPR (0.44) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL28634892 | 0.82 | KMT2A (0.65) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL29160656 | 0.81 | EGFR (0.51) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL29160660 | 0.80 | SPR (0.50) | SPRMEN1KMT2AKDM4EHPGD | |
| SCHEMBL28629849 | 0.80 | KMT2A (0.49) | MEN1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL29123415 | 0.79 | SPR (0.43) | SPRMEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429332-B | 3-substituted indole derivative, preparation method thereof and application thereof in antitumor drugs | 长春工业大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-113429332-A | 3-substituted indole derivative, preparation method thereof and application thereof in antitumor drugs | 长春工业大学 | 2021-09-24 | — | — | CN | disclosed |