Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642927 | 0.91 | ALDH1A1 (0.40) | S1PR4KMT2AMAPK14MAPTCYP19A1 | |
| SCHEMBL18484534 | 0.90 | KMT2A (0.43) | S1PR4KMT2AMAPK14MAPTCYP19A1 | |
| SCHEMBL28632021 | 0.84 | MEN1 (0.46) | KMT2AMAPK14MAPTCYP19A1CYP11B1 | |
| SCHEMBL19205686 | 0.77 | MMP2 (0.36) | KMT2AMAPK14MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19205688 | 0.77 | MMP2 (0.36) | KMT2AMAPK14MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18448565 | 0.77 | KMT2A (0.43) | S1PR4KMT2AMAPK14MAPTALDH1A1 | |
| SCHEMBL18483189 | 0.77 | ACHE (0.44) | KMT2AMAPK14MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18447793 | 0.76 | CYP11B1 (0.56) | MAPTCYP19A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL18448545 | 0.75 | MAPT (0.57) | KMT2AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18448239 | 0.74 | ALDH1A1 (0.49) | KMT2AMAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026050-B | Novel compounds as ROR gamma modulators | 格兰马克药品股份有限公司 | 2021-04-30 | — | — | CN | disclosed |