Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27976255 | 0.74 | MAOB (0.30) | — | |
| SCHEMBL2423528 | 0.70 | OPRM1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL28040037 | 0.69 | GAA (0.37) | TSHR | |
| SCHEMBL28537875 | 0.66 | MAOB (0.36) | — | |
| SCHEMBL4236763 | 0.66 | MAOB (0.36) | — | |
| SCHEMBL20211715 | 0.66 | HSD11B1 (0.36) | — | |
| SCHEMBL28044919 | 0.65 | MAOB (0.35) | OPRL1 | |
| SCHEMBL16695048 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL6548185 | 0.64 | KDM1A (0.33) | — | |
| Urea SCHEMBL10593912 | 0.64 | MAOB (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354651-B | Pyrazolo [1,5-a ] quinazoline derivative and application thereof in preparation of medicines | 四川大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-113354651-A | Pyrazolo [1,5-a ] quinazoline derivative and application thereof in preparation of medicines | 四川大学 | 2021-09-07 | — | — | CN | disclosed |