Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16563717 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL28650107 | 0.79 | LTB4R (0.35) | — | |
| SCHEMBL6976089 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL27869621 | 0.78 | CYP4F2 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL7958215 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL13141285 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11190008 | 0.71 | L3MBTL1 (0.47) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL11136653 | 0.70 | F11 (0.46) | SMN1; SMN2MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL31063616 | 0.69 | CA1 (0.51) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL31063163 | 0.69 | CA1 (0.48) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430973-B | ROR gamma modulators | 领先制药控股公司 | 2021-09-21 | — | — | CN | disclosed |